Chemoenzymatic approaches to lycorine-type Amaryllidaceae alkaloids: total syntheses of ent -lycoricidine, 3- epi-ent -lycoricidine and 4-deoxy-3- epi-ent -lycoricidine
Matveenko, Maria; Kokas, Okanya; Banwell, Martin; Willis, Anthony
Description
The readily available and enzymatically derived cis-1,2-dihydrocatechol 4 has been elaborated, over 11 steps including an Overman rearrangement, into the non-natural enantiomer, (-)-1, of the alkaloid lycoricidine [(+)-1]. Related chemistries have provided analogues 18, 19, and 26.
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2007 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/33319 |
| Source: | Organic Letters |
| DOI: | 10.1021/ol701552r |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Matveenko_Chemoenzymatic_approaches_to_2007.pdf | 65.05 kB | Adobe PDF | Request a copy |
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