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CD4+ T Cells Modulate Expansion and Survival but Not Functional Properties of Effectror and Memory CD8+ T Cells Induced by Malaria Sporozoites

Overstreet, Michael G; Chen, Yun-Chi; Cockburn, Ian; Tse, Sze-Wah; Zavala, Fidel

Description

CD4+ helper T cells are critical orchestrators of immune responses to infection and vaccination. During primary responses, naïve CD8+ T cells may need "CD4 help" for optimal development of memory populations. The immunological factors attributed to CD4 h

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/33298
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0015948

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