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A mutation in a chromosome condensin II subunit, kleisin, specifically disrupts T cell development

Gosling, Katharine; Makaroff, Lydia; Theodoratos, Angelo; Kim, Yong Hee; Whittle, Belinda; Rui, Lixin; Wu, Hua; Hong, Nancy A; Kennedy, Gavin; Fritz, Julie-Anne; Yates (previously Loy), Adele; Goodnow, Christopher; Fahrer, Aude

Description

Condensins are ubiquitously expressed multiprotein complexes that are important for chromosome condensation and epigenetic regulation of gene transcription, but whose specific roles in vertebrates are poorly understood. We describe a mouse strain, nessy,

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/33155
Source: PNAS - Proceedings of the National Academy of Sciences of the United States of America
DOI: 10.1073/pnas.0704870104

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