Reproductive history and pancreatic cancer incidence and mortality in a cohort of postmenopausal women
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Stevens, Richard J; Roddam, Andrew W; Green, Jane; Pirie, Kirstin; Bull, Diana; Reeves, Gillian K; Beral, Valerie; Banks, Emily; Million Women Study, Collaborators
Description
There is inconsistent evidence about the effect of reproductive history on women's risk of pancreatic cancer. In the Million Women Study, a prospective cohort of middle-aged women in the United Kingdom, we examined associations between reproductive history and pancreatic cancer incidence and mortality, controlling for age, socioeconomic status, geographic region, body mass index, smoking, and history of diabetes. During 7.1 million person-years of follow-up in 995,192 postmenopausal women,...[Show more]
dc.contributor.author | Stevens, Richard J | |
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dc.contributor.author | Roddam, Andrew W | |
dc.contributor.author | Green, Jane | |
dc.contributor.author | Pirie, Kirstin | |
dc.contributor.author | Bull, Diana | |
dc.contributor.author | Reeves, Gillian K | |
dc.contributor.author | Beral, Valerie | |
dc.contributor.author | Banks, Emily | |
dc.contributor.author | Million Women Study, Collaborators | |
dc.date.accessioned | 2015-12-08T22:23:41Z | |
dc.date.available | 2015-12-08T22:23:41Z | |
dc.identifier.issn | 1055-9965 | |
dc.identifier.uri | http://hdl.handle.net/1885/32972 | |
dc.description.abstract | There is inconsistent evidence about the effect of reproductive history on women's risk of pancreatic cancer. In the Million Women Study, a prospective cohort of middle-aged women in the United Kingdom, we examined associations between reproductive history and pancreatic cancer incidence and mortality, controlling for age, socioeconomic status, geographic region, body mass index, smoking, and history of diabetes. During 7.1 million person-years of follow-up in 995,192 postmenopausal women, there were 1,182 incident pancreatic cancers. Pancreatic cancer incidence and mortality did not vary significantly with age at menarche, number of children, age at first birth, breast-feeding, type of menopause, age at menopause, or time since menopause. Any effect of reproductive history and pancreatic cancer risk in women is likely to be weak, if it exists at all. | |
dc.publisher | American Association for Cancer Research | |
dc.source | Cancer Epidemiology, Biomarkers and Prevention | |
dc.subject | Keywords: adult; anamnesis; article; breast feeding; cancer incidence; cancer mortality; cancer risk; cohort analysis; female; follow up; human; major clinical study; menarche; menopause; pancreas cancer; postmenopause; priority journal; prospective study; United K | |
dc.title | Reproductive history and pancreatic cancer incidence and mortality in a cohort of postmenopausal women | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 18 | |
dc.date.issued | 2009 | |
local.identifier.absfor | 111706 - Epidemiology | |
local.identifier.ariespublication | u4637548xPUB97 | |
local.type.status | Published Version | |
local.contributor.affiliation | Stevens, Richard J, University of Oxford | |
local.contributor.affiliation | Roddam, Andrew W, University of Oxford | |
local.contributor.affiliation | Green, Jane, University of Oxford | |
local.contributor.affiliation | Pirie, Kirstin, University of Oxford | |
local.contributor.affiliation | Bull, Diana, University of Oxford | |
local.contributor.affiliation | Reeves, Gillian K, University of Oxford | |
local.contributor.affiliation | Beral, Valerie, University of Oxford | |
local.contributor.affiliation | Banks, Emily, College of Medicine, Biology and Environment, ANU | |
local.contributor.affiliation | Million Women Study, Collaborators, NHS Breast Screening Centres | |
local.bibliographicCitation.issue | 5 | |
local.bibliographicCitation.startpage | 1457 | |
local.bibliographicCitation.lastpage | 1460 | |
local.identifier.doi | 10.1158/1055-9965.EPI-08-1134 | |
dc.date.updated | 2016-02-24T11:17:05Z | |
local.identifier.scopusID | 2-s2.0-66549101734 | |
local.identifier.thomsonID | 000266081500017 | |
Collections | ANU Research Publications |
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