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2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA A receptors

Karim, Nasiara; Curmi, John; Gavande, Navnath; Johnston, Graham A R; Hanrahan, Jane R; Tierney, Mary (Louise); Chebib, Mary

Description

BACKGROUND AND PURPOSE Flavonoids are known to have anxiolytic and sedative effects mediated via actions on ionotropic GABA receptors. We sought to investigate this further. EXPERIMENTAL APPROACH We evaluated the effects of 2′-methoxy-6-methylflavone (2

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/32783
Source: British Journal of Pharmacology
DOI: 10.1111/j.1476-5381.2011.01604.x

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