Skip navigation
Skip navigation

The functional design of the rotary enzyme ATP synthase is consistent with maximum entropy production

Dewar, Roderick; Juretic, D; Zupanovic, P

Description

We show that the molecular motor ATP synthase has evolved in accordance with the statistical selection principle of Maximum Shannon Entropy and one of its corollaries, Maximum Entropy Production. These principles predict an optimal angular position for the ATP-binding transition close to the experimental value; an inverse relation between the optimal gearing ratio and the proton motive force (pmf); optimal operation at an inflection point in the curve of ATP synthesis rate versus pmf, enabling...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/32541
Source: Chemical Physics Letters
DOI: 10.1016/j.cplett.2006.08.095

Download

File Description SizeFormat Image
01_Dewar_The_functional_design_of_the_2006.pdf236.54 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator