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The Brain Reserve Hypothesis, Brain Atrophy and Ageing

Christensen, Helen; Parslow, Ruth; Maller, Jerome; Mackinnon, Andrew; Sachdev, Perminder Singh; Anstey, Kaarin


Background: Researchers have used the concept of brain reserve to explain the dissociation between pathological brain damage and cognitive and functional performance. A variety of brain reserve hypotheses exist, and different empirical strategies have been employed to investigate these variants. Objective: The study investigates (i) the relationship between measures of brain burden (atrophy, white matter hyperintensities (WMH)) and measures of reserve (education, creativity, and intelligence);...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Gerontology
DOI: 10.1159/000096482


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