Skip navigation
Skip navigation

Feedback Inhibition of Pantothenate Kinase Regulates Pantothenol Uptake by the Malaria Parasite

Lehane, Adele; Marchetti, Rosa; Spry, Christina; Van Schalkwyk, Donelly; Teng, Rongwei; Kirk, Kiaran; Saliba, Kevin

Description

To survive, the human malaria parasite Plasmodium falciparum must acquire pantothenate (vitamin B5) from the external medium. Pantothenol (provitamin B5) inhibits parasite growth by competing with pantothenate for pantothenate kinase, the first enzyme in

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/32459
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M704610200

Download

File Description SizeFormat Image
01_Lehane_Feedback_Inhibition_of_2007.pdf606.88 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator