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Neuroendocrine mechanisms controlling female puberty:new approaches, new concepts

Ojeda, Sergio R; Roth, Christian; Mungenast, Alison; Herger, Sabine; Mastronardi, Claudio; Parent, Anne-Simone; Lomniczi, Alejandro; Jung, Heike


Sexual development and mature reproductive function are controlled by a handful of neurones that, located in the basal forebrain, produce the decapeptide luteinizing hormone releasing hormone (LHRH). LHRH is released into the portal system that connects the hypothalamus to the pituitary gland and act on the latter to stimulate the synthesis and release of gonadotrophin hormones. The pubertal activation of LHRH release requires coordinated changes in excitatory and inhibitory inputs to...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
Source: International Journal of Andrology
DOI: 10.1111/j.1365-2605.2005.00619.x


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