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Effect of 30 mCi radioiodine on multinodular goiter previously treated with recombinant human thyroid-stimulating hormone

Da Paz Filho, Gilberto; Mesa - Junior, CO; Olandoski, M.; Woellner, L C; Goedert, CA; Boguszewski, Cesar Luiz; Carvalho, CA; Graf, Hans


Recombinant human thyroid-stimulating hormone (rhTSH) enhances 131I uptake, permitting a decrease in radiation for the treatment of multinodular goiter (MNG). Our objective was to evaluate the safety and efficacy of a single 0.1-mg dose of rhTSH, followed by 30 mCi 131I, in patients with MNG. Seventeen patients (15 females, 59.0 ± 13.1 years), who had never been submitted to 131I therapy, received a single 0.1-mg injection of rhTSH foHowed by 30 mCi 131I on the next day. Mean basal thyroid...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Brazilian Journal of Medical and Biological Research
DOI: 10.1590/S0100-879X2006005000186


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