Eosinophils from Lineage-Ablated Delta dblGATA Bone Marrow Progenitors: The dblGATA Ehancer in the Promoter of GATA-1 Is Not Essential for Differentiation Ex Vivo
Dyer, Kimberley D; Czapiga, Meggan; Foster, Barbara; Foster, Paul S; Kang, Elizabeth M; Lappas, Courtney M.; Moser, Jennifer M; Naumann, Nora; Percopo, Caroline M.; Siegel, Steven J; Swartz, Jonathan M; Ting-De Ravin, SukSee; Rosenberg, Helene F
Description
A critical role for eosinophils in remodeling of allergic airways was observed in vivo upon disruption of the dblGATA enhancer that regulates expression of GATA-1, which resulted in an eosinophil-deficient phenotype in the ΔdblGATA mouse. We demonstrate
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2007 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/31666 |
| Source: | Journal of Immunology |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Dyer_Eosinophils_from_2007.pdf | 115.44 kB | Adobe PDF | Request a copy | |
| 02_Dyer_Eosinophils_from_2007.pdf | 353.41 kB | Adobe PDF | Request a copy |
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