Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates
-
Altmetric Citations
Shahab, Muhammad; Mastronardi, Claudio; Seminara, Stephanie B.; Crowley, William F.; Ojeda, Sergio R; Plant, Tony M.
Description
To further study the role of GPR54 signaling in the onset of primate puberty, we used the monkey to examine the ability of kisspeptin-10 to elicit the release of gonadotropin-releasing hormone (GnRH) precociously, and we describe the expression of GPR54 and KiSS-1 in the hypothalamus during the peripubertal period. Agonadal juvenile male monkeys were implanted with a lateral cerebroventricular cannula and a jugular vein catheter. The responsiveness of the juvenile pituitary to endogenous GnRH...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2005 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/31523 |
Source: | PNAS - Proceedings of the National Academy of Sciences of the United States of America |
DOI: | 10.1073/pnas.0409822102 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Shahab_Increased_hypothalamic_GPR54_2005.pdf | 2.06 MB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator