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Maturation of Auditory Brainstem Projections and Calyces in the Congenitally deaf( dn/dn ) mouse

Youssoufian, Monique; Couchman, Kiri; Shivdasani, Mohit N.; Paolini, Antonio G.; Walmsley, Bruce


The deaf dn/dn mouse is a valuable model of human congenital deafness. In this study we used the lipophylic dye DiA to trace auditory nerve and cochlear nucleus projections in the dn/dn mouse. In both normal and deaf mice, the ipsilateral projections from the anteroventral cochlear nucleus (AVCN) to the lateral superior olive (LSO), and the contralateral projections from the AVCN to the medial nucleus of the trapezoid body (MNTB) were intact. With age, there was a noted increase in the...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Comparative Neurology
DOI: 10.1002/cne.21566


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