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Correlates of protective immunity in poxvirus infection: where does antibody stand?

Panchanathan, Vijay; Chaudhri, Geeta; Karupiah, Gunasegaran


Even though smallpox has been eradicated, the threat of accidental or intentional release has highlighted the fact there is little consensus about correlates of protective immunity or immunity against re-infection with the causative poxvirus, variola virus (VARV). As the existing vaccine for smallpox has unacceptable rates of side effects and complications, new vaccines are urgently needed. Surrogate animal models of VARV infection in humans, including vaccinia virus (VACV) and ectromelia virus...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Immunology and Cell Biology
DOI: 10.1038/sj.icb.7100118


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