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A mechanism for Ikaros regulation of human globin geneswitching

Keys, Janelle R.; Tallack, Michael R.; Zhan, Ye; Papathanasiou, Panagiotis; Goodnow, Christopher; Gaensler, Karin M; Crossley, Merlin; Dekker, Job; Perkins, Andrew C.

Description

The human β globin locus consists of an upstream LCR and functional genes arranged sequentially in the order of their expression during development: 5′-HBE1, HBG2, HBG1, HBD, HBB-3′. Haemoglobin switching entails the successive recruitment of these g

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/31071
Source: British Journal of Haematology
DOI: 10.1111/j.1365-2141.2008.07065.x

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