A mechanism for Ikaros regulation of human globin geneswitching
The human β globin locus consists of an upstream LCR and functional genes arranged sequentially in the order of their expression during development: 5′-HBE1, HBG2, HBG1, HBD, HBB-3′. Haemoglobin switching entails the successive recruitment of these g
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|Source:||British Journal of Haematology|
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