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Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria

Vanslambrouck, Jessica M.; Broer, Angelika; Thavyogarajah, Thuvaraka; Holst, Jeff; Bailey, Charles; Broer, Stefan; Rasko, John Edward


Renal maturation occurs post-natally in many species and reabsorption capacity at birth can vary substantially from the mature kidney. However, little is known regarding the maturation of amino acid transport mechanisms, despite the well-known physiological state of developmental iminoglycinuria. Commonly seen during early infancy, developmental iminoglycinuria is a transient version of the persistent inherited form of the disorder, referred to as iminoglycinuria, and manifests as a urinary...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Biochemical Journal
DOI: 10.1042/BJ20091667


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