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SiLEncing SLE: the power and promise of small noncoding RNAs

Rigby, Robert; Garcia De Vinuesa, Maria Carola


Dysregulation of the RNA silencing machinery has been implicated in systemic lupus erythematosus pathogenesis. Although microRNA profiling may prove to be a useful diagnostic and prognostic tool for a notoriously heterogeneous disease, manipulation of RNA interference emerges as a powerful and potentially specific means to correct dysregulated gene expression in systemic lupus erythematosus patients.

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Current Opinion in Rheumatology
DOI: 10.1097/BOR.0b013e328304b45e


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