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Eosinophil trafficking in allergy and asthma

Rosenberg, Helene F; Phipps, Simon; Foster, Paul S


Blood eosinophilia and tissue eosinophilia are characteristic features of allergic inflammation and asthma, conditions associated with prominent production of TH2 cytokines IL-4, IL-5, and IL-13. In this review, we will consider recent advances in our understanding of the molecular mechanisms that promote expansion and differentiation of eosinophil progenitors in bone marrow, eosinophil recruitment in response to chemokine receptor 3 agonists eosinophil transit mediated by specific...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Journal of Allergy and Clinical Immunology
DOI: 10.1016/j.jaci.2007.03.048


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