Brain-derived neurotrophic factor modulates cell excitability in the mouse medial nucleus of the trapezoid body.
Neurotrophins are a large class of trophic factors located throughout the central nervous system. While the role of neurotrophins in neuronal survival and axon guidance is well known, their secondary role in modulating synaptic transmission and cell firing properties is largely unexplored. In this study we examined the expression of neurotrophins in the mouse medial nucleus of the trapezoid body (MNTB) and investigated the effect of exogenous brain-derived neurotrophic factor (BDNF) application...[Show more]
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|Source:||European Journal of Neuroscience|
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