The contribution of toll-like receptors to the pathogenesis of asthma
Phipps, Simon; Lam, Chuan En; Foster, Paul S; Matthaei, Klaus
Asthma is a major disease in the westernized world and its incidence has significantly increased over the past 40 years. Our understanding of the pathogenesis of asthma remains rudimentary, and for this reason, little has been accomplished by way of targeted intervention, either at a population level (to reduce the overall prevalence) or at an individual level (to treat the cause). Instead, the management strategy currently in use relies on broad-spectrum anti-inflammatory agents, generally...[Show more]
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