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Unravelling the association of partial T-cell immunodeficiency and immune dysregulation

Liston, Adrian; Enders, Anselm; Siggs, Owen


Partial T-cell immunodeficiencies constitute a heterogeneous cluster of disorders characterized by an incomplete reduction in T-cell number or activity. The immune deficiency component of these diseases is less severe than that of the severe T-cell immunodeficiencies and therefore some ability to respond to infectious organisms is retained. Unlike severe T-cell immunodeficiencies, however, partial immunodeficiencies are commonly associated with hyper-immune dysregulation, including...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Nature Reviews Immunology
DOI: 10.1038/nri2336


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