Differentiation of regulatory Foxp3+ T cells in the thymic cortex
Regulatory Foxp3+ T cells (TR) are indispensable for preventing autoimmune pathology in multiple organs and tissues. During thymic differentiation T cell receptor (TCR)-ligand interactions within a certain increased affinity range, in conjunction with γc
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|Source:||PNAS - Proceedings of the National Academy of Sciences of the United States of America|
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