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Biomechanics of human optic chiasmal compression: ex vivo experiment and finite element modelling

Wang, Xiaofei; Neely, Andrew; Jain, Neeranjali; Jain, Swaranjali; Jain, Sanjiv; Tahtali, Murat; McIlwaine, Gawn G.; Lueck, Christian


The mechanism of bitemporal hemianopia arising as a result of chiasmal compression is unknown. In this study, we combined an ex vivo experiment and finite element modelling (FEM) to investigate its potential mechanism. A cadaveric human optic chiasm was scanned using micro-CT before and after deformation by inflation of Foley catheter, to simulate tumour growth from beneath. The geometry of the same chiasm was reconstructed and simulated using finite element analysis. Chiasmal deformations were...[Show more]

CollectionsANU Research Publications
Date published: 2022
Type: Journal article
Source: Medicine in Novel Technology and Devices
DOI: 10.1016/j.medntd.2021.100113
Access Rights: Open Access


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