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Dendritic mechanisms controlling spike-timing dependent synaptic plasticity

Kampa, Bjoern; Letzkus, Johannes; Stuart, Gregory J


The ability of neurons to modulate the strength of their synaptic connections has been shown to depend on the relative timing of pre- and postsynaptic action potentials. This form of synaptic plasticity, called spike-timing-dependent plasticity (STDP), has become an attractive model for learning at the single-cell level. Yet, despite its popularity in experimental and theoretical neuroscience, the influence of dendritic mechanisms in the induction of STDP has been largely overlooked. Several...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Trends in Neurosciences
DOI: 10.1016/j.tins.2007.06.010


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