Potentiation of photodynamic therapy of cancer by complement: the effect of gamma-inulin
Host response elicited by photodynamic therapy (PDT) of cancerous lesions is a critical contributor to the clinical outcome, and complement system has emerged as its important element. Amplification of complement action was shown to improve tumour PDT response. In search of a clinically relevant complement activator for use as a PDT adjuvant, this study focused on γ-inulin and examined its effects on PDT response of mouse tumours. Intralesional γ-inulin (0.1 mg mouse-1) delivered immediately...[Show more]
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|Source:||British Journal of Cancer|
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