The Putative Role of Natural Killer Cells in Patients with Hepatitis C Virus-Related Hepatocellular Carcinoma
Hassona, Mona M; Radwan, Enas M; Abdelsameea, Eman; ESTAPHAN, Suzanne; Abd Elrhman, Heba E; Abdel-Samiee, Mohamed; Naguib, Mary
Background: Natural Killer (NK) cells have crucial roles in immune responses against malignant transformation including hepatocellular carcinoma (HCC). The NKG2D receptor has a critical role in the NK recognition of target cells. Aim: We assessed NKG2D receptor expression as a diagnostic biomarker for HCC detection and progression in Egyptian patients with hepatitis C virus (HCV)-related HCC. Methods: We classified 81 patients into three groups: chronic hepatitis (21), cirrhotic (30) and HCC...[Show more]
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|Source:||Asia Pacific Journal of Cancer Prevention|
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