Skip navigation
Skip navigation

Neurological complication related to atrial myxomas

Baird-Gunning, Jonathan; Lalloo, Shivendra; Lueck, Christian; Das, Chandi

Description

Objectives Atrial myxoma is a rare neoplasm that accounts for approximately 50% of primary cardiac tumours. Neurological complications of atrial myxoma include stroke from tumour embolization and aneurysm formation. The pathogenesis of aneurysm formation is unclear. We present a patient whose myxoma was diagnosed following an embolic stroke and who was then diagnosed with the typical cerebral aneurysms related to the tumour. Case A 62 year old woman presented with left facial weakness and...[Show more]

dc.contributor.authorBaird-Gunning, Jonathan
dc.contributor.authorLalloo, Shivendra
dc.contributor.authorLueck, Christian
dc.contributor.authorDas, Chandi
dc.contributor.editorMatthew C Kiernan
dc.coverage.spatialGold Coast, Australia
dc.date.accessioned2023-02-20T04:50:03Z
dc.date.created09/05/17-12/05/17
dc.identifier.issn0022-3050
dc.identifier.urihttp://hdl.handle.net/1885/285339
dc.description.abstractObjectives Atrial myxoma is a rare neoplasm that accounts for approximately 50% of primary cardiac tumours. Neurological complications of atrial myxoma include stroke from tumour embolization and aneurysm formation. The pathogenesis of aneurysm formation is unclear. We present a patient whose myxoma was diagnosed following an embolic stroke and who was then diagnosed with the typical cerebral aneurysms related to the tumour. Case A 62 year old woman presented with left facial weakness and dysarthria. Physical examination confirmed the dysarthria and an upper motor neurone pattern of facial weakness. A non-contrast CT brain demonstrated an evolving ischaemic infarction in the right frontal lobe. Transthoracic echocardiography demonstrated an atrial myxoma, which was resected. Her husband reported she had mild cognitive changes and problems with mobility at a four-month follow-up. MRI brain at that point revealed multifocal aneurysmal dilatation of pial vessels, in addition to evidence of previous infarction and leptomeningeal siderosis from prior small SAH. Digital subtraction angiography revealed fusiform aneurysms associated with atrial myxoma Conclusions This case highlights both the recognised neurologic complications of atrial myxoma in a single patient and presents the characteristic angiographic findings. The diagnosis of cerebral aneurysms can be delayed up to five years. Evaluation should therefore be considered following a histologic diagnosis of atrial myxoma.
dc.format.mimetypeapplication/pdf
dc.language.isoen_AU
dc.publisherBMJ Group
dc.relation.ispartofseriesAnnual Scientific Meeting of the Australian-and-New-Zealand-Association-of-Neurologists (ANZAN) 2017
dc.rights© 2017 BMJ Group
dc.sourceJournal of Neurology, Neurosurgery & Psychiatry
dc.titleNeurological complication related to atrial myxomas
dc.typeConference paper
local.description.notesImported from ARIES
local.description.refereedYes
dc.date.issued2017
local.identifier.absfor320101 - Cardiology (incl. cardiovascular diseases)
local.identifier.ariespublicationu5369653xPUB6
local.publisher.urlhttps://jnnp.bmj.com/
local.type.statusPublished Version
local.contributor.affiliationBaird-Gunning, Jonathan, College of Health and Medicine, ANU
local.contributor.affiliationLalloo, Shivendra, Cig Young Hospital
local.contributor.affiliationLueck, Christian, College of Health and Medicine, ANU
local.contributor.affiliationDas, Chandi, Canberra Hospital
local.description.embargo2099-12-31
local.bibliographicCitation.startpage35
local.bibliographicCitation.lastpage35
local.identifier.doi10.1136/jnnp-2017-316074.94
dc.date.updated2021-12-02T05:05:45Z
CollectionsANU Research Publications

Download

File Description SizeFormat Image
e1.97.full.pdf35.68 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator