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Conservation and turnover of miRNAs and their highly complementary targets in early branching animals

Praher, Daniela; Zimmermann, Bob; Dnyansagar, Rohit; Miller, David J.; Moya, A.; Modepalli, Vengamanaidu; Fridrich, Arie; Sher, Daniel; Friis-Moller, Lene; Sundberg, Per; Forêt, Sylvain; Ashby, Regan


MicroRNAs (miRNAs) are crucial post-transcriptional regulators that have been extensively studied in Bilateria, a group comprising the majority of extant animals, where more than 30 conserved miRNA families have been identified. By contrast, bilaterian miRNA targets are largely not conserved. Cnidaria is the sister group to Bilateria and thus provides a unique opportunity for comparative studies. Strikingly, like their plant counterparts, cnidarian miRNAs have been shown to predominantly have...[Show more]

CollectionsANU Research Publications
Date published: 2021
Type: Journal article
Source: Proceedings of the Royal Society of London Series B: Biological Sciences
DOI: 10.1098/rspb.2020.3169
Access Rights: Open Access


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