Keller, Florence A; Breton, Jean-Didier; Schlichter, Remy; Poisbeau, Pierrick
In lamina II of the spinal dorsal horn, synaptic inhibition mediated by ionotropic GABAA and glycine receptors contributes to the integration of peripheral nociceptive messages. Whole-cell patch-clamp recordings were performed from lamina II neurons in spinal cord slices to study the properties of miniature IPSCs (mIPSCs) mediated by activation of GABA A and glycine receptors in immature (<30 d) and adult rats. Blockade of neurosteroidogenesis by...[Show more]
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