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DNA-Demethylase Regulated Genes Show Methylation-Independent Spatiotemporal Expression Patterns

Schumann, Ulrike; Lee, Joanne; Kazan, Kemal; Ayliffe, Michael; Wang, Mingbo


Recent research has indicated that a subset of defense-related genes is downregulated in the Arabidopsis DNA demethylase triple mutant rdd (ros1 dml2 dml3) resulting in increased susceptibility to the fungal pathogen Fusarium oxysporum. In rdd plants these downregulated genes contain hypermethylated transposable element sequences (TE) in their promoters, suggesting that this methylation represses gene expression in the mutant and that these sequences are actively demethylated in wild-type...[Show more]

CollectionsANU Research Publications
Date published: 2017
Type: Journal article
Source: Frontiers in Plant Science
DOI: 10.3389/fpls.2017.01449
Access Rights: Open Access


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