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Protein interactions involving the gamma2 large cytoplasmic loop of GABA A receptors modulate conductance

Everitt, Andrea; Seymour, Victoria; Curmi, John; Laver, Derek Rowland; Gage, Peter; Tierney, Mary (Louise)


Native GABAA channels display a single-channel conductance ranging between ∼10 and 90 pS. Diazepam increases the conductance of some of these native channels but never those of recombinant receptors, unless they are coexpressed with GABARAP. This traffi

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: FASEB Journal
DOI: 10.1096/fj.09-137042


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