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LABEL-FREE FUNCTIONAL IMAGING OF PLATELETS AT NANOSCALE

Zheng, Yujie

Description

Platelet is the key cellular machinery of a blood clot/thrombus. Platelet morphodynamics under fluid shear plays an essential role in the quantitative analysis of platelet dysfunction. The mechanical properties of platelets inform the formation of haemostatic plugs that have wide application in bleeding disorders and cardiovascular diseases. During clotting, individual platelets sense physical and biochemical agonists on their surface receptors that trigger the formation of membrane...[Show more]

CollectionsRestricted Theses
Date published: 2022
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/277982
DOI: 10.25911/MX5V-N948
Embargoed until: 2023-11-08

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