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Dna-binding and cytotoxicity of copper(I) complexes containing functionalized dipyridylphenazine ligands

Alsaedi, Sammar; Babgi, Bandar A; Abdellatif, Magda H; Arshad, Muhammad Nadeem; Emwas, Abdul-Hamid M; Jaremko, Mariusz; Humphrey, Mark; Asiri, Abdullah M; Hussien, Mostafa A


A set of copper(I) coordination compounds with general formula [CuBr(PPh3 )(dppz-R)] (dppz-R = dipyrido[3,2-a:2’,3’-c]phenazine (Cu-1), 11-nitrodipyrido[3,2-a:2’,3’-c]phenazine (Cu-2), 11-cyanodipyrido[3,2-a:2’,3’-c]phenazine (Cu-3), dipyrido[3,2-a:2’,3’-c]phenazine-11-phenone (Cu-4), 11,12-dimethyldipyrido[3,2-a:2’,3’-c]phenazine (Cu-5)) have been prepared and characterized by elemental analysis,1H-NMR and31P-NMR spectroscopies as well as mass spectrometry. The structure of Cu-1 was confirmed...[Show more]

CollectionsANU Research Publications
Date published: 2021
Type: Journal article
Source: Pharmaceutics
DOI: 10.3390/pharmaceutics13050764
Access Rights: Open Access


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