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CD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates

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Norbury, Christopher; Basta, Sameh; Donohue, Keri B; Tscharke, David; Princiotta, Michael; Berglund, Peter; Gibbs, James; Bennink, Jack R; Yewdell, Jonathan W

Description

"Cross-priming" describes the activation of naïve CD8 + T cells by professional antigen-presenting cells that have acquired viral or tumor antigens from "donor" cells. Antigen transfer is believed to be mediated by donor cell-derived molecular chaperones

dc.contributor.authorNorbury, Christopher
dc.contributor.authorBasta, Sameh
dc.contributor.authorDonohue, Keri B
dc.contributor.authorTscharke, David
dc.contributor.authorPrinciotta, Michael
dc.contributor.authorBerglund, Peter
dc.contributor.authorGibbs, James
dc.contributor.authorBennink, Jack R
dc.contributor.authorYewdell, Jonathan W
dc.date.accessioned2015-12-07T22:53:09Z
dc.identifier.issn0036-8075
dc.identifier.urihttp://hdl.handle.net/1885/27732
dc.description.abstract"Cross-priming" describes the activation of naïve CD8 + T cells by professional antigen-presenting cells that have acquired viral or tumor antigens from "donor" cells. Antigen transfer is believed to be mediated by donor cell-derived molecular chaperones
dc.publisherAmerican Association for the Advancement of Science
dc.sourceScience
dc.subjectKeywords: Antigens; Proteins; Tumors; Vaccines; Cross-priming; Rational design; Cells; CD8 antigen; chaperone; ligand; peptide; proteasome; tumor antigen; vaccine; virus antigen; antigen; immune system; animal cell; animal experiment; animal model; animal tissue; a
dc.titleCD8+ T Cell Cross-Priming via Transfer of Proteasome Substrates
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume304
dc.date.issued2004
local.identifier.absfor110704 - Cellular Immunology
local.identifier.ariespublicationu4325460xPUB53
local.type.statusPublished Version
local.contributor.affiliationNorbury, Christopher, National Institutes of Health
local.contributor.affiliationBasta, Sameh, National Institutes of Health
local.contributor.affiliationDonohue, Keri B, Pennsylvania State University
local.contributor.affiliationTscharke, David, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationPrinciotta, Michael, National Institutes of Health
local.contributor.affiliationBerglund, Peter, National Institutes of Health
local.contributor.affiliationGibbs, James, National Institutes of Health
local.contributor.affiliationBennink, Jack R, National Institutes of Health
local.contributor.affiliationYewdell, Jonathan W, National Institute of Allergy & Infectious Diseases
local.description.embargo2037-12-31
local.bibliographicCitation.startpage1318
local.bibliographicCitation.lastpage1321
local.identifier.doi10.1126/science.1096378
dc.date.updated2015-12-07T12:37:39Z
local.identifier.scopusID2-s2.0-2542574206
CollectionsANU Research Publications

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