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Chlorinated Flame-Retardant Dechlorane 602 Potentiates Type 2 Innate Lymphoid Cells and Exacerbates Airway Inflammation

Zhou, Pengcheng; Zheng, Ting; Li, Yunping; Zhang, Xin; Feng, Jinhong; Wei, Yunbo; Wang, Hao; Yao, Yin; Gong, Fang; Tian, Wenjing; Sun, Lingyun; Liu, Zheng; Zhao, Bin; Yu, Di


Chlorinated flame-retardant dechloranes are emerging substitutes for restricted flame retardants. Recent studies have demonstrated that they are accumulated in wildlife and detectable in humans; however, their effects on human health are poorly understood. Here, for the first time, we revealed that widely used chlorinated flame-retardant dechlorane 602 (Dec 602) exacerbated airway inflammation in two mouse models induced by house dust mite (HDM) or IL-33, respectively. Deteriorated airway...[Show more]

CollectionsANU Research Publications
Date published: 2021
Type: Journal article
Source: Environmental Science and Technology
DOI: 10.1021/acs.est.0c03758


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