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Physico-chemical modelling of target depletion during hybridization on oligonulceotide microarrays

Burden, Conrad; Binder, Hans


The effect of target molecule depletion from the supernatant solution is incorporated into a physico-chemical model of hybridization on oligonucleotide microarrays. Two possible regimes are identified: local depletion, in which depletion by a given probe

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Physical Biology
DOI: 10.1088/1478-3975/7/1/016004


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