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Toxins not neutralized by brown snake antivenom

Judge, Roopwant; Henry, Peter J.; Mirtschin, Peter; Jelinek, George; Wilce, Jacqueline

Description

The Australian snakes of the genus Pseudonaja (dugite, gwardar and common brown) account for the majority of snake bite related deaths in Australia. Without antivenom treatment, the risk of mortality is significant. There is an accumulating body of evidence to suggest that the efficacy of the antivenom is limited. The current study investigates the protein constituents recognized by the antivenom using 2-DE, immuno-blot techniques and rat tracheal organ bath assays. The 2-DE profiles for all...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/27456
Source: Toxicology and Applied Pharmacology
DOI: 10.1016/j.taap.2005.09.010

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