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New protocols for the synthesis of 3,4-annulated and 4-substituted quinolines from β-bromo α,β-unsaturated aldehydes and 1-bromo-2-nitrobenzene or 2-bromoacetanilide

Some, Surajit; Ray, Jayanta K; Banwell, Martin; Jones, Matthew


The palladium[0]-mediated Ullmann cross-coupling of readily available β-bromo-α,β-unsaturated aldehydes of the general form 2 with 1-bromo-2-nitrobenzene (3, X = Br) delivers products, 4, that undergo reductive cyclization to novel quinolines (5) upon

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Tetrahedron Letters
DOI: 10.1016/j.tetlet.2007.03.078


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