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Stereocontrolled synthesis of (S)-Y-fluoroleucine

Padmakshan, Dharshana; Bennett, Simon; Easton, Christopher; Otting, Gottfried

Description

Starting with (S)-leucine, the corresponding γ-fluoride 8 has been prepared in a stereocontrolled fashion, by exploiting methods for the direct side-chain bromination of amino acid derivatives and silven(I) fluoride as the fluorinating reagent.

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/26662
Source: Synlett
DOI: 10.1055/s-2007-977420

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