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Integrating structured biological data by kernel maximum mean discrepancy

Borgwardt, Karsten; Gretton, Arthur; Rasch, Malte J.; Kriegel, Hans-Peter; Schoelkopf, Bernhard; Smola, Alexander

Description

Motivation: Many problems in data integration in bioinformatics can be posed as one common question: Are two sets of observations generated by the same distribution? We propose a kernel-based statistical test for this problem, based on the fact that two distributions are different if and only if there exists at least one function having different expectation on the two distributions. Consequently we use the maximum discrepancy between function means as the basis of a test statistic. The Maximum...[Show more]

CollectionsANU Research Publications
Date published: 2006
Type: Journal article
URI: http://hdl.handle.net/1885/26612
Source: Bioinformatics
DOI: 10.1093/bioinformatics/btl242

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