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No interaction between the serotonin transporter polymorphism (5-HTTLPR) and childhood adversity or recent stressful life events on symptoms of depression: results from two community surveys

Chipman, Phillip; Jorm, Anthony F; Prior, M; Sanson, A; Smart, Diana; Tan, Susan (Xiaoyun); Easteal, Simon

Description

In this study we investigated interactions between the 5-HTTLPR genotype and environmental risk factors (G x E) on symptoms of depression in two large Australian community samples of adolescents and young adults. We postulated that a significant interaction between the 5-HTTLPR genotype and environmental risk factors of childhood adversity or stressful life events on symptoms of depression would be observed in subjects with at least one short allele (s/l or s/s) compared with subjects with no...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
URI: http://hdl.handle.net/1885/26355
Source: American Journal of Medical Genetics, Part B: Neuropsychiatric
DOI: 10.1002/ajmg.b.30480

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