Anti-neutrophil cytoplasmic antibody-associated systemic vasculitis: Nature or nurture?
This review examines the environmental and genetic contributions to the anti-neutrophil cytoplasmic antibody-associated systemic vasculitides. The dominant environmental risk factors appear to be silica exposure for all three syndromes, and vitamin D deficiency is strongly suggested by the latitude and ultraviolet radiation gradient observed for Wegener's granulomatosis and Churg-Strauss syndrome. Genetic factors are generally not very strong, consistent with the rarity of these conditions in...[Show more]
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|Source:||Internal Medicine Journal|
|01_Gatenby_Anti-neutrophil_cytoplasmic_2011.pdf||121.52 kB||Adobe PDF||Request a copy|
|02_Gatenby_Anti-neutrophil_cytoplasmic_2011.pdf||188.95 kB||Adobe PDF||Request a copy|
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