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Nutritional Control of Reproductive Status in Honeybees via DNA Methylation

Kucharski, Robert; Maleszka, Joanna; Foret, Sylvain; Maleszka, Ryszard


Fertile queens and sterile workers are alternative forms of the adult female honeybee that develop from genetically identical larvae following differential feeding with royal jelly. We show that silencing the expression of DNA methyltransferase Dnmt3, a key driver of epigenetic global reprogramming, in newly hatched larvae led to a royal jelly-like effect on the larval developmental trajectory; the majority of Dnmt3 small interfering RNA-treated individuals emerged as queens with fully...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Science
DOI: 10.1126/science.1153069


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