NOD2: Ethnic and geographic differences
Investigations into the inheritance of the three risk alleles; R702W, G908R and 1007fsInsC in NOD2 associated with susceptibility to Crohn's disease have demonstrated a remarkable amount of heterogeneity across ethnicities and populations, with regional variation across Europe for example, suggesting local founder effects. In non-Caucasian populations Crohn's disease continues to increase in incidence but this increase appears not to be a consequence of variation in NOD2, further advancing the...[Show more]
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|Source:||World Journal of Gastroenterology|
|01_Cavanaugh_NOD2:_Ethnic_and_geographic_2006.pdf||344.46 kB||Adobe PDF||Request a copy|
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