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The effects of methylene blue infusion on gastric tonometry and intestinal fatty acid binding protein levels in septic shock patients

Van Haren, Frank; Pickkers, Peter; Foudraine, Norbert; Heemskerk, Suzanne; Sleigh, J; van der Hoeven, Johannes G


Objective: We prospectively studied the effect of methylene blue (MB) infusion on gastric mucosal metabolism perfusion ratio, assessed by gastric tonometry, and on mucosal cell damage, assessed by urinary levels of intestinal fatty acid binding protein, in septic shock patients. Methods: Methylene blue (MB) infusion (1 mg/kg per hour) during 4 hours in 10 consecutive patients with a proven or suspected bacterial infection and with severe vasodilatory shock, defined as a mean arterial pressure...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Journal of Critical Care
DOI: 10.1016/j.jcrc.2010.02.008


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