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Early Trabecular Compensation in Femoral Bone of the Diabetic NOD*B10 foz/foz Mouse

Fleming, Madeleine


Bone mineral density (BMD) does not adequately predict bone fracture risk in contemporary type 2 diabetic patients. The rising prevalence of younger onset diabetes and obesity together reveal an endemic fragility for diabetic patients with equal or higher BMD than non-diabetics. Other factors contribute to this paradoxical fracture risk jeopardising skeletal acquisition and lifetime bone remodelling capacity. NOD*B10 mice are susceptible to obesity and diabetes unlike the BALB/c strain...[Show more]

CollectionsOpen Access Theses
Date published: 2022
Type: Thesis (MPhil)
DOI: 10.25911/FRT9-2S17


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