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Occult bone marrow involvement in patients with diffuse large B-cell lymphoma: results of a pilot study

Talaulikar, Dipti; Dahlstrom, Jane; Shadbolt, Bruce; McNiven, Michelle; Broomfield, Amy; Pidcock, Michael


Aims: It is known that advanced stage disease in diffuse large B-cell lymphoma (DLBCL) confers a poor prognosis, and staging investigations are routinely performed at diagnosis, including a bone marrow (BM) biopsy. However, examination of the BM is usually limited to routine light microscopy, with the role of ancillary investigations remaining unestablished. The aim of this pilot study was to estimate the incidence of occult marrow involvement using flow cytometry, immunohistochemistry and...[Show more]

CollectionsANU Research Publications
Date published: 2007
Type: Journal article
Source: Pathology
DOI: 10.1080/00313020701684417


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