Landscape of DNA methylation on the marsupial x
DNA methylation plays a key role in maintaining transcriptional silence on the inactive X chromosome of eutherian mammals. Beyond eutherians, there are limited genome wide data on DNA methylation from other vertebrates. Previous studies of X borne genes in various marsupial models revealed no differential DNA methylation of promoters between the sexes, leading to the conclusion that CpG methylation plays no role in marsupial X-inactivation. Using reduced representation bisulfite sequencing, we...[Show more]
|Collections||ANU Research Publications|
|Source:||Molecular Biology and Evolution|
|Access Rights:||Open Access|
|01_Waters_Landscape_of_DNA_methylation_2018.pdf||658.04 kB||Adobe PDF|
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