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Loss of sensory input increases the intrinsic excitability of layer 5 pyramidal neurons in rat barrel cortex.

Breton, Jean-Didier; Stuart, Gregory J


Development of the cortical map is experience dependent, with different critical periods in different cortical layers. Previous work in rodent barrel cortex indicates that sensory deprivation leads to changes in synaptic transmission and plasticity in layer 2/3 and 4. Here, we studied the impact of sensory deprivation on the intrinsic properties of layer 5 pyramidal neurons located in rat barrel cortex using simultaneous somatic and dendritic recording. Sensory deprivation was achieved by...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Journal of Physiology
DOI: 10.1113/jphysiol.2009.180943


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