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Comparison of the validity of smear and culture conversion as a prognostic marker of treatment outcome in patients with multidrug-resistant tuberculosis

Alene, Kefyalew Addis; Viney, Kerri; Yi, Hengzhong; McBryde, Emma; Yang, Kunyun; Bai, Liqiong; Gray, Darren; Xu, Zuhui; Clements, Archie


Background The World Health Organization (WHO) has conditionally recommended the use of sputum smear microscopy and culture examination for the monitoring of multidrug-resistant tuberculosis (MDR-TB) treatment. We aimed to assess and compare the validity of smear and culture conversion at different time points during treatment for MDR-TB, as a prognostic marker for end-of-treatment outcomes. Methods We undertook a retrospective observational cohort study using data obtained from Hunan...[Show more]

CollectionsANU Research Publications
Date published: 2018
Type: Journal article
Source: PLOS ONE (Public Library of Science)
DOI: 10.1371/journal.pone.0197880
Access Rights: Open Access


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